
We Reviewed the Top 20 Brands to Find the Best Quality Weight Loss Supplement in 2025
Discover the Top-Ranked Weight Loss Supplements for 2025

With so many people looking to better manage their weight and feel more in control of their appetite, it's no surprise that weight support supplements have gained serious attention.
Over the past few months, we've noticed a surge of interest in natural products designed to complement a healthy lifestyle by supporting metabolism, satiety, and energy levels. In response, we’ve taken a deep dive into the top 20 most talked-about formulas and emerging ingredients.
The result? A curated list of the 5 weight management supplements available in the U.S. for 2025—each selected for its quality, composition, and customer satisfaction.

Elisabeth Larsen, Research Specialist
With extensive experience in the field of supplements, Elisabeth stands out as a leading author and researcher. Her expertise is highlighted in our Top 5 Weight Loss Supplements review article.

Elisabeth Larsen, Research Specialist
With extensive experience in the field of supplements, Elisabeth stands out as a leading author and researcher. Her expertise is highlighted in our Top 5 Weight Loss Supplements review article.
What are Weight Loss Supplements?
Weight loss supplements are dietary formulations developed to support individuals in their weight management efforts, typically by helping with appetite control and curbing cravings.
Commonly included compounds such as green coffee bean extract, green tea extract, apple cider vinegar, and raspberry ketones have each been studied for their potential roles in appetite regulation and fat metabolism.
While these supplements are not a substitute for a balanced diet and regular physical activity, they may offer additional support when used as part of a healthy lifestyle.

Weight Loss Supplements May Help With:
What To Look For In A Weight Loss Supplement
Opt for supplements that feature ingredients with clinical or preclinical research supporting their role in weight management. Botanicals such as green tea extract, green coffee bean, caffeine from natural sources, apple cider vinegar, and raspberry ketones are commonly used for their potential to support metabolism, appetite regulation, and energy balance.*
Trustworthy products disclose all active ingredients and their exact dosages. This transparency allows users to evaluate whether the formulation aligns with evidence-based standards and ensures there are no hidden proprietary blends or underdosed components.
Choose products that are manufactured in certified U.S. facilities following Good Manufacturing Practices (GMP). Independent third-party testing adds an extra layer of assurance regarding the supplement’s purity, potency, and safety.
A reputable brand stands behind its product. Look for companies that offer at least a 60-day money-back guarantee, allowing you to try the supplement risk-free and demonstrating the manufacturer's confidence in their formulation.
What To Avoid
Be cautious of formulas packed with artificial colors, preservatives, or non-essential fillers. These may not only dilute the active ingredients but also introduce unwanted reactions or sensitivities.
Avoid supplements that promise rapid or effortless weight loss. Products that market themselves as “miracle solutions” often lack scientific integrity. Instead, rely on brands that position their products as tools to complement, not replace, a healthy lifestyle.
While affordability matters, extremely low prices may signal cost-cutting measures that affect ingredient quality, dosage accuracy, or manufacturing standards. Prioritize value and safety over just price.
What We Looked Out For:
A comparison of the best weight loss supplements

Meo Nutrition

Natnect

OLLY

Nature's Bounty

EPN Supplements
Type
Capsules
Capsules
Gummies
Capsules
Capsules
Key ingredients
Green Coffee Bean & EGCG
EGCG
Apple Cider Vinegar
Sinetrol
R. ketone & A. mango
Third-party tested
Money back guarantee
24/7 customer service
Price point
$$
$$$
$$
$
$$$
The Top 5 Weight Loss Supplements in 2025


9.7/10
TOTAL RANKING
A+
OVERALL GRADE
PROS
- Comprehensive blend of EGCG, G.cofee, R.ketone & more.
- Promotes easier weight loss.
- Clean, potent and natural formula.
- Produced in the USA at an FDA licensed facility.
- 60 day, risk free, money back guarantee.
- Recommended by doctors.
- Subscription and bulk discounts offered.
- Third-party tested/certificate of analysis (COA).
- No artificial ingredients.
- Ships from Texas.
- Over 400.000+ customers.
CONS
- Due to high demand, it may sometimes be sold out.
- Can only be found online.
After reviewing the top weight management supplements on the market, one product that clearly stood out was Meo Nutrition’s Shred GLP-1.
This formula brings together a carefully selected blend of green coffee bean, green tea extract rich in EGCG, raspberry ketones, garcinia cambogia, and caffeine—ingredients commonly used to support metabolism, appetite control, and energy levels as part of a balanced lifestyle.*
We appreciated the simplicity and focus of this blend. It avoids unnecessary fillers and sticks to well-researched, plant-derived compounds. The formula is vegan, non-GMO, and free from the top 9 allergens, which adds an extra layer of reassurance for those with dietary sensitivities.
Beyond the formulation itself, Meo Nutrition impressed us with their commitment to quality. All their supplements are manufactured in Utah in GMP-certified facilities, with third-party testing to ensure purity and consistency. They’re also NSF Certified for Sport and UDAF Organic Certified, which speaks volumes about their manufacturing standards.
Shipping was prompt (we received ours the next day), and their customer service team responded quickly and helpfully to all inquiries. As for price, Shred GLP-1 is very competitively positioned, with per-capsule costs starting at just $0.66—and dropping to $0.42 when purchased in bulk.
If you're looking for a clean, thoughtfully formulated supplement to support your weight goals, Shred GLP-1 by Meo Nutrition is a top-tier choice worth considering.


Conclusion
After reviewing the top weight management supplements on the market, one product that clearly stood out was Meo Nutrition’s Shred GLP-1.
This formula brings together a carefully selected blend of green coffee bean, green tea extract rich in EGCG, raspberry ketones, garcinia cambogia, and caffeine—ingredients commonly used to support metabolism, appetite control, and energy levels as part of a balanced lifestyle.*
We appreciated the simplicity and focus of this blend. It avoids unnecessary fillers and sticks to well-researched, plant-derived compounds. The formula is vegan, non-GMO, and free from the top 9 allergens, which adds an extra layer of reassurance for those with dietary sensitivities.
Beyond the formulation itself, Meo Nutrition impressed us with their commitment to quality. All their supplements are manufactured in Utah in GMP-certified facilities, with third-party testing to ensure purity and consistency. They’re also NSF Certified for Sport and UDAF Organic Certified, which speaks volumes about their manufacturing standards.
Shipping was prompt (we received ours the next day), and their customer service team responded quickly and helpfully to all inquiries. As for price, Shred GLP-1 is very competitively positioned, with per-capsule costs starting at just $0.66—and dropping to $0.42 when purchased in bulk.
If you're looking for a clean, thoughtfully formulated supplement to support your weight goals, Shred GLP-1 by Meo Nutrition is a top-tier choice worth considering.
2. Natnect GLP-1 Supplement



9.0/10
TOTAL RANKING
A
OVERALL GRADE
PROS
- Comprehensive blend of Eriocitrin, EGCG & other herbal extracts.
- 100% vegan & non-GMO.
- Made in the USA.
- Positive reviews.
CONS
- Costly at $35+ per bottle.
- No third-party testing information.
- Limited money-back guarantees.
GLP-1 Supplement by Natnect is positioned as a premium option in the weight management category, offering a curated formula that includes Eriocitrin, EGCG (from green tea), and other herbal extracts commonly used to support metabolism and appetite regulation.*
The product has earned praise for delivering a clean, plant-based product—100% vegan, non-GMO, and manufactured in the USA.
We were particularly interested in the inclusion of Eriocitrin, a citrus flavonoid studied for its potential antioxidant and metabolic support properties, alongside green tea catechins and other botanicals that may aid energy balance when combined with diet and exercise.
While the formula appears well-designed, there are a few drawbacks worth noting. At over $35 per bottle, Natnect GLP-1 is on the higher end of the price spectrum, and the company does not currently provide clear information on third-party testing.
Additionally, their return policy lacks flexibility compared to some competitors, offering only limited money-back guarantees.
Overall, Natnect GLP-1 is a strong contender with a clean and innovative ingredient profile.


Conclusion
GLP-1 Supplement by Natnect is positioned as a premium option in the weight management category, offering a curated formula that includes Eriocitrin, EGCG (from green tea), and other herbal extracts commonly used to support metabolism and appetite regulation.*
The product has earned praise for delivering a clean, plant-based product—100% vegan, non-GMO, and manufactured in the USA.
We were particularly interested in the inclusion of Eriocitrin, a citrus flavonoid studied for its potential antioxidant and metabolic support properties, alongside green tea catechins and other botanicals that may aid energy balance when combined with diet and exercise.
While the formula appears well-designed, there are a few drawbacks worth noting. At over $35 per bottle, Natnect GLP-1 is on the higher end of the price spectrum, and the company does not currently provide clear information on third-party testing.
Additionally, their return policy lacks flexibility compared to some competitors, offering only limited money-back guarantees.
Overall, Natnect GLP-1 is a strong contender with a clean and innovative ingredient profile.
3. OLLY Metabolism Gummy Rings



8.7/10
TOTAL RANKING
B+
OVERALL GRADE
PROS
- Blend of Apple Cider Vinegar, Vitamin B12 & Chromium.
- Easy to take for people who dislike pills.
- US-made, without synthetic colors or flavors.
CONS
- Small blend.
- No money-back guarantee.
- Some may dislike the taste and texture.
OLLY Metabolism Gummy Rings offer a convenient and approachable option for those looking to support their metabolism through a supplement that fits easily into daily routines—especially for individuals who prefer gummies over capsules.
This formula includes a focused blend of Apple Cider Vinegar, Vitamin B12, and Chromium—ingredients commonly associated with supporting energy production and metabolic function.*
OLLY is known for its accessible, user-friendly products, and this one follows suit. It's made in the USA and free from synthetic colors and artificial flavors, aligning with the brand’s clean-label approach.
One of the biggest advantages of OLLY's Metabolism Gummy Rings is how easy they are to take—no pills or water required—which can be a meaningful factor for daily compliance.
That said, the blend is relatively minimal compared to other metabolism-focused supplements on the market, and it may not meet the expectations of those seeking a more comprehensive formulation.
Additionally, the product does not come with a money-back guarantee, which might be a consideration for first-time buyers. Some users have also reported that the taste and texture may not appeal to everyone.


Conclusion
OLLY Metabolism Gummy Rings offer a convenient and approachable option for those looking to support their metabolism through a supplement that fits easily into daily routines—especially for individuals who prefer gummies over capsules.
This formula includes a focused blend of Apple Cider Vinegar, Vitamin B12, and Chromium—ingredients commonly associated with supporting energy production and metabolic function.*
OLLY is known for its accessible, user-friendly products, and this one follows suit. It's made in the USA and free from synthetic colors and artificial flavors, aligning with the brand’s clean-label approach.
One of the biggest advantages of OLLY's Metabolism Gummy Rings is how easy they are to take—no pills or water required—which can be a meaningful factor for daily compliance.
That said, the blend is relatively minimal compared to other metabolism-focused supplements on the market, and it may not meet the expectations of those seeking a more comprehensive formulation.
Additionally, the product does not come with a money-back guarantee, which might be a consideration for first-time buyers. Some users have also reported that the taste and texture may not appeal to everyone.
4. Nature's Bounty Metabolism Booster



8.2/10
TOTAL RANKING
B
OVERALL GRADE
PROS
- Comprehensive Sinetrol and Black Gunger blend.
- Money-back guarantee.
- Made in the USA.
- Affordable.
CONS
- No transparent testing information.
- Mixed comments.
Nature’s Bounty Metabolism Booster combines affordability with a well-rounded ingredient profile, making it an appealing option for those seeking a budget-friendly supplement to support their metabolic wellness.
This product features a blend of Sinetrol®—a citrus-based extract studied for its potential role in fat metabolism—and Black Ginger, a traditional herb increasingly explored for its possible benefits in energy support and physical performance.*
The formulation is made in the USA and backed by a money-back guarantee, offering peace of mind for first-time users.
Nature’s Bounty has long been a recognizable name in the supplement industry, and this metabolism booster reflects the brand’s accessible approach to wellness.
The price point is particularly attractive for those looking to try a metabolism-support formula without making a large upfront investment.
However, while the product checks many boxes, it lacks transparency when it comes to third-party testing, and the company does not provide detailed quality assurance documentation online. Customer reviews are also somewhat mixed—while some users report noticeable benefits, others mention no changes.


Conclusion
Nature’s Bounty Metabolism Booster combines affordability with a well-rounded ingredient profile, making it an appealing option for those seeking a budget-friendly supplement to support their metabolic wellness.
This product features a blend of Sinetrol®—a citrus-based extract studied for its potential role in fat metabolism—and Black Ginger, a traditional herb increasingly explored for its possible benefits in energy support and physical performance.*
The formulation is made in the USA and backed by a money-back guarantee, offering peace of mind for first-time users.
Nature’s Bounty has long been a recognizable name in the supplement industry, and this metabolism booster reflects the brand’s accessible approach to wellness.
The price point is particularly attractive for those looking to try a metabolism-support formula without making a large upfront investment.
However, while the product checks many boxes, it lacks transparency when it comes to third-party testing, and the company does not provide detailed quality assurance documentation online. Customer reviews are also somewhat mixed—while some users report noticeable benefits, others mention no changes.
5. EPN Supplements Skinny Girl Glow



7.9/10
TOTAL RANKING
C+
OVERALL GRADE
PROS
- Blend of Raspberry ketone, African mango & more.
- Third-party tested.
- US-made, Non-GMO & Hypoallergenic.
CONS
- Small number of reviews.
- Proprietary blend.
- Limited guarantees.
EPN Supplements’ Skinny Girl Glow is a metabolism-support supplement that brings together a curated selection of ingredients often associated with weight management and wellness support.
With a focus on natural extracts, this product includes raspberry ketones, African mango, and additional botanicals commonly used to complement diet and lifestyle efforts.*
While the ingredient selection is promising, it’s worth noting that the formula is delivered as a proprietary blend, which means the exact dosages of some of the components are not disclosed. This can make it harder for users to assess how the product aligns with research-backed quantities.
Additionally, the product has a relatively small number of customer reviews available, making it harder to gauge consistent user experiences. The brand also offers limited money-back guarantees compared to more established names in the category.
That said, Skinny Girl Glow may be a worthwhile option for those looking for a clean-label, US-made supplement with third-party testing and a focus on botanical ingredients.


Conclusion
EPN Supplements’ Skinny Girl Glow is a metabolism-support supplement that brings together a curated selection of ingredients often associated with weight management and wellness support.
With a focus on natural extracts, this product includes raspberry ketones, African mango, and additional botanicals commonly used to complement diet and lifestyle efforts.*
While the ingredient selection is promising, it’s worth noting that the formula is delivered as a proprietary blend, which means the exact dosages of some of the components are not disclosed. This can make it harder for users to assess how the product aligns with research-backed quantities.
Additionally, the product has a relatively small number of customer reviews available, making it harder to gauge consistent user experiences. The brand also offers limited money-back guarantees compared to more established names in the category.
That said, Skinny Girl Glow may be a worthwhile option for those looking for a clean-label, US-made supplement with third-party testing and a focus on botanical ingredients.
CITATIONS
- Hursel R, Viechtbauer W, Westerterp-Plantenga MS. The effects of green tea on weight loss and weight maintenance: a meta-analysis. Int J Obes (Lond). 2009 Sep;33(9):956-61. doi: 10.1038/ijo.2009.135. Epub 2009 Jul 14. PMID: 19597519.
- Hasan F, Hamilton K, Angadi S, Kranz S. The Effects of Vinegar/Acetic Acid Intake on Appetite Measures and Energy Consumption: A Systematic Literature Review. Curr Dev Nutr. 2022 Jun 14;6(Suppl 1):285. doi: 10.1093/cdn/nzac053.026. PMCID: PMC9193460.
- Hursel R, Viechtbauer W, Dulloo AG, Tremblay A, Tappy L, Rumpler W, Westerterp-Plantenga MS. The effects of catechin-rich teas and caffeine on energy expenditure and fat oxidation: a meta-analysis. Obes Rev. 2011 Jul;12(7):e573-81. doi: 10.1111/j.1467-789X.2011.00862.x. Epub 2011 Mar 2. PMID: 21366839.
- Jazinaki MS, Nosrati M, Chambari M, Jamialahmadi T, Sahebkar A. The Effects of Raspberry Consumption on Glycemic Control and Inflammation Markers in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Curr Dev Nutr. 2024 May 3;8(6):102161. doi: 10.1016/j.cdnut.2024.102161. PMID: 38860149; PMCID: PMC11163149.
- Thom E. The effect of chlorogenic acid-enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese people. J Int Med Res. 2007 Nov-Dec;35(6):900-8. doi: 10.1177/147323000703500620. PMID: 18035001.
What You Will Learn:
- The benefits of a high quality weight loss supplement
- What to look for in a weight loss supplement
- The top 5 weight loss supplements

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[1] This website is owned and operated by Cosari® and Meo Nutrition® brands.
*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Note: The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a healthcare provider. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Results do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Trademarks utilized on our website belong to their respective owners and no implied or expressed endorsement of our website or services is intended. Rankings can be affected by the relationship Supplement Review has with our picks.

[1] This website is owned and operated by Cosari® and Meo Nutrition® brands.
*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Note: The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a healthcare provider. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Results do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Trademarks utilized on our website belong to their respective owners and no implied or expressed endorsement of our website or services is intended. Rankings can be affected by the relationship Smarter Choices has with our picks.
© 2025 supplement-review.co
All Rights Reserved.