We Reviewed the Top 20 Brands to Find the Best Quality Saffron in 2025
Discover the Top-Ranked Saffron Supplements for 2025
Saffron has dazzled cultures around the globe for centuries—prized in ancient Persia for its brilliant hue and exotic flavor, heralded in traditional medicine for its uplifting and restorative powers.
Today, it’s rapidly emerging as a modern wellness star, celebrated for its potential to support mood balance, curb cravings, and promote overall vitality. After fielding countless questions from readers eager to harness saffron’s benefits, our team embarked on an in-depth investigation into the market’s most promising supplements.
The result? A carefully curated list of five standout products in the US that have truly earned their stripes. Read on to discover which saffron supplements rose to the top—and why you just might want them in your daily health regimen during 2025.
Elisabeth Larsen, Research Specialist
With extensive experience in the field of supplements, Elisabeth stands out as a leading author and researcher. Her expertise is highlighted in our Top 5 Saffron Supplement review article.
Elisabeth Larsen, Research Specialist
With extensive experience in the field of supplements, Elisabeth stands out as a leading author and researcher. Her expertise is highlighted in our Top 5 Saffron Supplement review article.
What is Saffron?
Saffron extracts are derived from the dried stigmas of the Crocus sativus flower, historically cherished in Persian, Greek, and Ayurvedic traditions.
Its bioactive compounds—particularly crocin and safranal—may affect mood by modulating neurotransmitters like serotonin and dopamine. Modern research highlights saffron’s potential for supporting mood, providing antioxidative effects, and much more...
Saffron Supplement May Help With:
What To Look For In A Saffron Supplement
Look for a daily serving of at least 30 mg of pure saffron, the minimum proven effective amount in clinical studies. Ensure the listed dosage refers specifically to saffron—and not just filler ingredients—since some brands dilute their products to cut costs.
Choose supplements manufactured in the United States, where strict quality controls help ensure product safety and consistency. Additionally, seek out third-party lab testing to verify purity, potency, and absence of contaminants.
Opt for a saffron supplement that backs its claims with a clear money-back policy. A 60-day guarantee lets you try the product risk-free and return it if it doesn’t meet your expectations.
Reputable brands make it easy to return a product if it fails to meet your needs. Be wary of companies with convoluted return processes or unclear refund policies that complicate getting your money back.
What To Avoid
Steer clear of supplements packed with unnecessary fillers, binders, or artificial ingredients. These may dilute the potency of saffron and could introduce unwanted side effects.
Ignore any product claiming to cure specific conditions or promising unrealistic results. Supplements should support overall health without masquerading as medical treatments. Always consult your healthcare provider before beginning any new supplement.
While affordability can be appealing, rock-bottom prices may indicate lower quality or inadequate testing. Look for transparent labeling and reputable brands to ensure you’re getting a safe, effective supplement.
What We Looked Out For:
A comparison of the best saffron supplements
Meo Nutrition
Resciency
Youtheory
Nootropics Depot
Olly
Type
Capsule
Liposomal
Capsule
Capsule
Gummy
Daily dose of saffron
177 mg
88.5 mg
28 mg
30 mg
30 mg
Third-party tested
Money back guarantee
24/7 customer service
Price point
$$
$$
$$
$$
$$
The Top 5 Saffron Supplements in 2025
9.7/10
TOTAL RANKING
A+
OVERALL GRADE
PROS
- 177 mg of pure Saffron extract per day.
- Produced in the USA at an FDA licensed facility.
- 60-day, risk-free, money-back guarantee.
- Recommended by doctors.
- Subscription and bulk discounts offered.
- Third-party tested/certificate of analysis (COA).
- No artificial ingredients.
- Ships from Texas.
- Over 400.000+ customers.
CONS
- Due to high demand, it may sometimes be sold out.
- Can only be found online.
After reviewing the top 20 saffron supplements, our favorite by far was Meo Nutrition Saffron.
Their saffron formula offers tremendous value—featuring a pure, simple composition with a quality backed up by independent third-party testing.
It delivers 177 mg of premium saffron extract per day split in 2 servings and is vegan, Non-GMO, and free of the top 9 allergens.
Beyond the product’s science-backed approach and quality ingredients, we were impressed by the fast shipping (ours arrived the next day) and responsive customer support; the chat box team consistently replied quickly to any questions.
When it comes to pricing, Meo Nutrition Saffron is also very competitive, costing around $0.66 per capsule, and it can drop even lower—$0.42 per capsule—when purchased in bulk.
It’s garnered numerous positive reviews online, where users praise its ease of use and effectiveness.
Finally, all Meo Nutrition supplements are manufactured in Utah under GMP-certified, NSF sports-approved, and UDAF Organic-certified conditions, so you can trust each step of their production process.
Conclusion
After reviewing the top 20 saffron supplements, our favorite by far was Meo Nutrition Saffron.
Their saffron formula offers tremendous value—featuring a pure, simple composition with a quality backed up by independent third-party testing.
It delivers 177 mg of premium saffron extract per day split in 2 servings and is vegan, Non-GMO, and free of the top 9 allergens.
Beyond the product’s science-backed approach and quality ingredients, we were impressed by the fast shipping (ours arrived the next day) and responsive customer support; the chat box team consistently replied quickly to any questions.
When it comes to pricing, Meo Nutrition Saffron is also very competitive, costing around $0.66 per capsule, and it can drop even lower—$0.42 per capsule—when purchased in bulk.
It’s garnered numerous positive reviews online, where users praise its ease of use and effectiveness.
Finally, all Meo Nutrition supplements are manufactured in Utah under GMP-certified, NSF sports-approved, and UDAF Organic-certified conditions, so you can trust each step of their production process.
2. Resciency Liposomal Saffron
9.0/10
TOTAL RANKING
A
OVERALL GRADE
PROS
- Liposomal formula for better absorption.
- Convenient to take.
- 88.5mg of Saffron per 2ml.
- Additional herbal extracts.
CONS
- May be harder to dose precisely.
- Lacks clear testing information.
- Some may dislike the taste of liposomal formulations.
Resciency is building a name in the supplement space, and its Liposomal Saffron has gained attention for its innovative delivery system.
By encapsulating 88.5 mg of saffron extract (per 2 ml) in liposomes, Resciency aims to enhance nutrient absorption and bioavailability.
This formula also includes additional herbal extracts and, for many, proves convenient to take on a daily basis.
However, liposomal supplements can make precise dosing trickier, and the flavor may be off-putting for some.
Additionally, Resciency does not provide clear, publicly available testing information, which could leave certain customers wanting more transparency.
Despite these drawbacks, this product’s unique delivery mechanism and potent saffron content earn it a strong position in our roundup—especially for those seeking enhanced absorption.
Conclusion
Resciency is building a name in the supplement space, and its Liposomal Saffron has gained attention for its innovative delivery system.
By encapsulating 88.5 mg of saffron extract (per 2 ml) in liposomes, Resciency aims to enhance nutrient absorption and bioavailability.
This formula also includes additional herbal extracts and, for many, proves convenient to take on a daily basis.
However, liposomal supplements can make precise dosing trickier, and the flavor may be off-putting for some.
Additionally, Resciency does not provide clear, publicly available testing information, which could leave certain customers wanting more transparency.
Despite these drawbacks, this product’s unique delivery mechanism and potent saffron content earn it a strong position in our roundup—especially for those seeking enhanced absorption.
3. Youtheory Saffron
8.7/10
TOTAL RANKING
B+
OVERALL GRADE
PROS
- Sold on popular marketplaces.
- Simple & clean formula.
- Contains additional botanicals.
CONS
- Lower dose than most other brands.
- No money-back guarantee.
Youtheory Saffron supplement is another widely available saffron option on popular marketplaces—making it convenient to purchase.
The formula is fairly straightforward, featuring saffron alongside a few additional botanicals like Ashwagandha and Rhodiola.
However, the Ashwagandha and Rhodiola addition may be there to compensate for the lower Saffron dosage. In fact, the supplement is considerably lower in Saffron than many competing brands, which may limit its effectiveness for some individuals.
Another consideration is the lack of a money-back guarantee, so if you’re seeking reassurance or a flexible return policy, you’ll want to factor that in.
Overall, if you prefer a simple, clean formula from a readily accessible brand, Youtheory Saffron might fit the bill—but bear in mind the lower dose and the absence of a refund option.
Conclusion
Youtheory Saffron supplement is another widely available saffron option on popular marketplaces—making it convenient to purchase.
The formula is fairly straightforward, featuring saffron alongside a few additional botanicals like Ashwagandha and Rhodiola.
However, the Ashwagandha and Rhodiola addition may be there to compensate for the lower Saffron dosage. In fact, the supplement is considerably lower in Saffron than many competing brands, which may limit its effectiveness for some individuals.
Another consideration is the lack of a money-back guarantee, so if you’re seeking reassurance or a flexible return policy, you’ll want to factor that in.
Overall, if you prefer a simple, clean formula from a readily accessible brand, Youtheory Saffron might fit the bill—but bear in mind the lower dose and the absence of a refund option.
4. Nootropics Depot Saffron
8.2/10
TOTAL RANKING
B
OVERALL GRADE
PROS
- High-potency extract.
- Third-party tested.
- Made in the USA.
CONS
- Limited guarantees.
- Lower dosage than most brands.
Nootropics Depot is a recognized brand among those seeking cognitively supportive supplements, and their Saffron stands out for its high-potency extract (minimum 7.5% crocins and 1% safranals).
Additionally, the company provides third-party testing, offering more confidence in quality and purity.
However, it contains a lower dosage than many competitors, which may reduce its potential effectiveness despite the potency of the extracts.
Moreover, there are limited guarantees which could be a drawback for those who prioritize return policies and refund options.
Overall, if you value standardized potency and verifiable testing, Nootropics Depot Saffron remains a worthwhile choice—just be mindful of the dose and guarantee limitations.
Conclusion
Nootropics Depot is a recognized brand among those seeking cognitively supportive supplements, and their Saffron stands out for its high-potency extract (minimum 7.5% crocins and 1% safranals).
Additionally, the company provides third-party testing, offering more confidence in quality and purity.
However, it contains a lower dosage than many competitors, which may reduce its potential effectiveness despite the potency of the extracts.
Moreover, there are limited guarantees which could be a drawback for those who prioritize return policies and refund options.
Overall, if you value standardized potency and verifiable testing, Nootropics Depot Saffron remains a worthwhile choice—just be mindful of the dose and guarantee limitations.
5. OLLY Hello Happy
7.9/10
TOTAL RANKING
C+
OVERALL GRADE
PROS
- Gummies may offer convenience.
- Contains vitamin D.
- Gluten-free, Non-GMO & Hypoallergenic.
CONS
- Gummies may clump or melt together.
- Some may dislike the taste or texture.
- Lower Saffron dosage compared to competitors.
- Should not be combined with other vitamin D supplements.
OLLY’s Hello Happy has gained popularity thanks to its convenient gummy format, which also includes vitamin D for added nutritional support.
The brand has a strong following, and these gummies are gluten-free and non-GMO - all plus points for those with dietary restrictions.
However, gummies can clump or melt together if exposed to heat, and some individuals may dislike their taste or texture.
Moreover, the amount of saffron per gummy is quite low, compared to the relatively moderate-high vitamin D content.
Because Hello Happy already provides vitamin D, it’s best to avoid combining it with other high-dose vitamin D supplements.
Overall, if you prefer a gummy for convenience and taste, OLLY Hello Happy could be a nice fit—just be mindful of potential clumping and overlapping vitamin D intake.
Conclusion
OLLY’s Hello Happy has gained popularity thanks to its convenient gummy format, which also includes vitamin D for added nutritional support.
The brand has a strong following, and these gummies are gluten-free and non-GMO - all plus points for those with dietary restrictions.
However, gummies can clump or melt together if exposed to heat, and some individuals may dislike their taste or texture.
Moreover, the amount of saffron per gummy is quite low, compared to the relatively moderate-high vitamin D content.
Because Hello Happy already provides vitamin D, it’s best to avoid combining it with other high-dose vitamin D supplements.
Overall, if you prefer a gummy for convenience and taste, OLLY Hello Happy could be a nice fit—just be mindful of potential clumping and overlapping vitamin D intake.
CITATIONS
- Marx, Wolfgang et al. “Effect of saffron supplementation on symptoms of depression and anxiety: a systematic review and meta-analysis.” Nutrition reviews vol. 77,8 (2019): 557-571. doi:10.1093/nutrit/nuz023
- Lian, Jinrong et al. “Effects of saffron supplementation on improving sleep quality: a meta-analysis of randomized controlled trials.” Sleep medicine vol. 92 (2022): 24-33. doi:10.1016/j.sleep.2022.03.001
- Asbaghi, Omid et al. “The effect of saffron supplementation on blood glucose and lipid profile: A systematic review and meta-analysis of randomized controlled trials.” Complementary therapies in medicine vol. 47 (2019): 102158. doi:10.1016/j.ctim.2019.07.017
- Moravej Aleali, Armaghan et al. “The effect of hydroalcoholic Saffron (Crocus sativus L.) extract on fasting plasma glucose, HbA1c, lipid profile, liver, and renal function tests in patients with type 2 diabetes mellitus: A randomized double-blind clinical trial.” Phytotherapy research : PTR vol. 33,6 (2019): 1648-1657. doi:10.1002/ptr.6351
- Abedi, Ali et al. “Effect of saffron supplementation on oxidative stress markers (MDA, TAC, TOS, GPx, SOD, and pro-oxidant/antioxidant balance): An updated systematic review and meta-analysis of randomized placebo-controlled trials.” Frontiers in medicine vol. 10 1071514. 1 Feb. 2023, doi:10.3389/fmed.2023.1071514
- Ghaderi, Amir et al. “The effects of saffron (Crocus sativus L.) on mental health parameters and C-reactive protein: A meta-analysis of randomized clinical trials.” Complementary therapies in medicine vol. 48 (2020): 102250. doi:10.1016/j.ctim.2019.102250
- Tsolaki, Magda et al. “Efficacy and Safety of Crocus sativus L. in Patients with Mild Cognitive Impairment: One Year Single-Blind Randomized, with Parallel Groups, Clinical Trial.” Journal of Alzheimer's disease : JAD vol. 54,1 (2016): 129-33. doi:10.3233/JAD-160304
- Farokhnia, Mehdi et al. “Comparing the efficacy and safety of Crocus sativus L. with memantine in patients with moderate to severe Alzheimer's disease: a double-blind randomized clinical trial.” Human psychopharmacology vol. 29,4 (2014): 351-9. doi:10.1002/hup.2412
What You Will Learn:
- The benefits of a high quality saffron supplement
- What to look for in a saffron supplement
- The top 5 saffron supplements
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Note: The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a healthcare provider. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Results do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Trademarks utilized on our website belong to their respective owners and no implied or expressed endorsement of our website or services is intended. Rankings can be affected by the relationship Supplement Review has with our picks.
[1] This website is owned and operated by Cosari® and Meo Nutrition® brands.
*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Note: The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a healthcare provider. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Results do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Trademarks utilized on our website belong to their respective owners and no implied or expressed endorsement of our website or services is intended. Rankings can be affected by the relationship Smarter Choices has with our picks.
© 2025 supplement-review.co
All Rights Reserved.