We Reviewed the Top 20 Brands to Find the Best Quality Nitric Oxide Booster in 2025
Discover the Top-Ranked Nitric Oxide Booster Supplements for 2025
Looking to take your workouts to the next level? One of the most popular ways to do it is with nitric oxide (NO) boosters. Studies suggest they can help improve blood flow, ramp up stamina, and bolster exercise tolerance. But not all NO supplements are created equal! So our team pored over research, tested the top 20 brands, and dissected user feedback to find the real standouts. Ready to crush your fitness goals? Check out our top 5 picks for the best nitric oxide supplements on the US market in 2025.
Elisabeth Larsen, Research Specialist
With extensive experience in the field of supplements, Elisabeth stands out as a leading author and researcher. Her expertise is highlighted in our Top 5 Nitric Oxide Booster review article.
Elisabeth Larsen, Research Specialist
With extensive experience in the field of supplements, Elisabeth stands out as a leading author and researcher. Her expertise is highlighted in our Top 5 Nitric Oxide Booster review article.
What are nitric oxide boosters?
Nitric oxide (NO) boosters are dietary supplements formulated to ramp up your body’s production of this vital vasodilator.
They typically feature amino acids like L-arginine and L-citrulline—both of which help spark NO synthesis—as well as natural ingredients such as beetroot. Boosting NO levels may enhance workout performance by improving blood flow and stamina.
Plus, better circulation supports healthy blood pressure and promotes normal blood flow to different body parts, making these supplements more than just pre-workout...
Nitric Oxide Boosters Can Help With:
What To Look For In A Nitric Oxide Boosting Supplement
You want to look for ingredients that are scientifically proven to support endogenous nitric oxide production. Examples include amino acids like L-arginine and citruline. Natural extracts from beetroot may also aid NO synthesis.
Ensure that the ingredients are in a sufficient amount to exert their potential benefits. For example, one of the most common ingredients in nitric oxide boosters - L-arginine should be at least 800mg per serving.
Make sure the product you select is actually made in the USA, where we have strict manufacturing quality standards. In addition, you want a supplement that is third-party tested, by an independent laboratory. This will help ensure high quality and safety.
Try to choose a supplement that offers a 100% money-back guarantee. Look for brands that offer at least a 60-day money-back guarantee. If you are not happy with your product, it should be easy to return your supplement. Avoid brands that make it very difficult to return a product or get a refund.
What To Avoid
Avoid supplements that contain unnecessary additives, fillers, or artificial ingredients. These can dilute the potency of the supplement and may cause adverse reactions in some individuals.
Beware of any supplements that claim their product treats or cures any specific disease or ailment, or promises miraculous, unrealistic, or misleading results. Always speak to your doctor before starting a new supplement routine.
Selecting the cheapest rather than the best quality can potentially do you more harm than good. If brands don’t identify certain ingredients or nutrients and their amounts in each dose, you could end up with an ineffective or potentially harmful supplement.
What We Looked Out For:
A comparison of the best nitric oxide boosters
Meo Nutrition
Havasu Nutrition
Nature's Pure Blend
Nutricost
humanN
Type
Capsule
Capsule
Capsule
Capsule
Capsule
Main Ingredients
L-arginine & L-citrulline
L-arginine & L-citrulline
L-arginine & L-citrulline
L-arginine & L-citrulline
Beetroot extract
Third-party tested
Money back guarantee
24/7 customer service
Price point
$$
$$
$$$
$
$$
The Top 5 Nitric Oxide Boosters in 2025
1. Meo Nutrition L-Arginine Plus
9.7/10
TOTAL RANKING
A+
OVERALL GRADE
PROS
- Clean, potent and natural formula.
- Produced in the USA at an FDA licensed facility.
- 60 day, risk free, money back guarantee.
- Recommended by doctors.
- Subscription and bulk discounts offered.
- Third-party tested/certificate of analysis (COA).
- No artificial ingredients.
- Ships from Texas.
- Over 400.000+ customers.
CONS
- Due to high demand, it may sometimes be sold out.
- Can only be found online.
After reviewing the top 20 nitric oxide boosters on the market, our clear top pick is Meo Nutrition’s L-Arginine Plus.
This carefully crafted formula stands out for its synergistic blend of L-Arginine, L-Citrulline, Niacin (Vitamin B3), and Beta-Alanine—all working together to support natural nitric oxide production, healthy blood flow, and enhanced exercise performance.*
L-Arginine Plus is produced under stringent standards in Utah. It’s GMP-certified, NSF sports-approved, and UDAF Organic Certified, so you can feel confident that each batch meets the highest quality benchmarks.
We also appreciate the brand’s quick shipping and prompt customer service: we received our order the next day, and any questions were answered swiftly via chat.
Many users report experiencing improved endurance, reduced muscle fatigue, and better tolerance for high-intensity workouts when incorporating L-Arginine+ into their daily routine.*
If you’re seeking a high-quality supplement that targets overall circulation, energy, and heart health, Meo Nutrition’s L-Arginine+ is a top-tier choice. Its blend of science-backed ingredients, combined with the brand’s dedication to purity and quality, makes it a worthy addition to any fitness or wellness regimen.*
Conclusion
After reviewing the top 20 nitric oxide boosters on the market, our clear top pick is Meo Nutrition’s L-Arginine Plus.
This carefully crafted formula stands out for its synergistic blend of L-Arginine, L-Citrulline, Niacin (Vitamin B3), and Beta-Alanine—all working together to support natural nitric oxide production, healthy blood flow, and enhanced exercise performance.*
L-Arginine Plus is produced under stringent standards in Utah. It’s GMP-certified, NSF sports-approved, and UDAF Organic Certified, so you can feel confident that each batch meets the highest quality benchmarks.
We also appreciate the brand’s quick shipping and prompt customer service: we received our order the next day, and any questions were answered swiftly via chat.
Many users report experiencing improved endurance, reduced muscle fatigue, and better tolerance for high-intensity workouts when incorporating L-Arginine+ into their daily routine.*
If you’re seeking a high-quality supplement that targets overall circulation, energy, and heart health, Meo Nutrition’s L-Arginine+ is a top-tier choice. Its blend of science-backed ingredients, combined with the brand’s dedication to purity and quality, makes it a worthy addition to any fitness or wellness regimen.*
2. Havasu Nutrition L-Arginine Capsules
9.0/10
TOTAL RANKING
A
OVERALL GRADE
PROS
- 1200 mg blend of L-arginine + citrulline.
- Fair return policy.
- Contains beetroot.
CONS
- Lacks third party testing.
- L-citrullune amount is relatively lower than the L-arginine.
Havasu Nutrition is a familiar name in the supplement world, often praised for its broad range of products and strong marketing presence. T
heir L-Arginine formula—which boasts 1200 mg of L-arginine and citrulline, plus added beetroot—has attracted quite a following for those seeking better circulation and workout support.
Beyond the appealing formula, Havasu Nutrition offers a fair return policy, which can be a reassuring factor for first-time buyers.
However, there are a couple of drawbacks worth noting. For one, the product lacks third-party testing, so there’s no independent verification of its purity or potency.
Additionally, the ratio of citrulline to L-arginine is on the lower side, which may not deliver as robust a synergistic effect compared to more balanced blends.
Overall, if you’re comfortable with the brand and don’t prioritize third-party testing or a perfectly balanced formula, Havasu Nutrition’s L-Arginine remains a good option.
Conclusion
Havasu Nutrition is a familiar name in the supplement world, often praised for its broad range of products and strong marketing presence. T
heir L-Arginine formula—which boasts 1200 mg of L-arginine and citrulline, plus added beetroot—has attracted quite a following for those seeking better circulation and workout support.
Beyond the appealing formula, Havasu Nutrition offers a fair return policy, which can be a reassuring factor for first-time buyers.
However, there are a couple of drawbacks worth noting. For one, the product lacks third-party testing, so there’s no independent verification of its purity or potency.
Additionally, the ratio of citrulline to L-arginine is on the lower side, which may not deliver as robust a synergistic effect compared to more balanced blends.
Overall, if you’re comfortable with the brand and don’t prioritize third-party testing or a perfectly balanced formula, Havasu Nutrition’s L-Arginine remains a good option.
3. Nature's Pure Blend Nitric Oxide Flow
8.7/10
TOTAL RANKING
B+
OVERALL GRADE
PROS
- Sold on popular marketplaces.
- Simple & clean formula.
- 1500 mg blend of L-arginine & L-citrullune.
CONS
- More expensive than more supplements.
- No third-party testing.
Nature’s Pure Blend Nitric Oxide Supplement is another well-known option in the circulation and workout-support category, largely because it’s widely available across popular marketplaces, making it easy and convenient to purchase.
One standout feature is its simple and clean formula, delivering a potent 1500 mg blend of L-arginine and L-citrulline—two amino acids known for their role in natural nitric oxide production. This straightforward approach has made the supplement a go-to choice for many health enthusiasts seeking extra help with blood flow and endurance.
However, despite its popularity, a couple of drawbacks keep it lower on our list. First, the price tag is higher than many other comparable supplements on the market, which may be off-putting if you’re looking for a more budget-friendly option.
Second, Nature’s Pure Blend Nitric Oxide Supplement does not appear to undergo any third-party testing, leaving customers without additional verification of its purity and potency.
Overall, it’s a decent product if you value a no-frills formula and convenience of purchase, but if you prefer a more affordable option or place a strong emphasis on third-party certifications, you might find better fits elsewhere.
Conclusion
Nature’s Pure Blend Nitric Oxide Supplement is another well-known option in the circulation and workout-support category, largely because it’s widely available across popular marketplaces, making it easy and convenient to purchase.
One standout feature is its simple and clean formula, delivering a potent 1500 mg blend of L-arginine and L-citrulline—two amino acids known for their role in natural nitric oxide production. This straightforward approach has made the supplement a go-to choice for many health enthusiasts seeking extra help with blood flow and endurance.
However, despite its popularity, a couple of drawbacks keep it lower on our list. First, the price tag is higher than many other comparable supplements on the market, which may be off-putting if you’re looking for a more budget-friendly option.
Second, Nature’s Pure Blend Nitric Oxide Supplement does not appear to undergo any third-party testing, leaving customers without additional verification of its purity and potency.
Overall, it’s a decent product if you value a no-frills formula and convenience of purchase, but if you prefer a more affordable option or place a strong emphasis on third-party certifications, you might find better fits elsewhere.
4. Nutricost Nitric Oxide Booster
8.2/10
TOTAL RANKING
B
OVERALL GRADE
PROS
- 2250mg blend of L-arginine & L-citrullune.
- Third-party tested.
- Made in the USA.
CONS
- Dosage may be too high for some as there are reports of side effects.
Nutricost Nitric Oxide Booster is another well-known option in the nitric oxide supplement space, offering a powerful 2250 mg blend of L-arginine and L-citrulline.
It’s also third-party tested and made in the USA, which adds a layer of assurance regarding quality and transparency.
What makes it stand out is the higher overall dosage compared to many other brands, potentially benefiting those looking for a stronger boost in circulation and exercise performance.
However, this potency may not be for everyone. Some users report side effects—like digestive discomfort or headaches—possibly tied to taking higher amounts of these amino acids.
Overall, if you’re seeking a strong formula and value third-party testing, Nutricost could be a solid pick.
Conclusion
Nutricost Nitric Oxide Booster is another well-known option in the nitric oxide supplement space, offering a powerful 2250 mg blend of L-arginine and L-citrulline.
It’s also third-party tested and made in the USA, which adds a layer of assurance regarding quality and transparency.
What makes it stand out is the higher overall dosage compared to many other brands, potentially benefiting those looking for a stronger boost in circulation and exercise performance.
However, this potency may not be for everyone. Some users report side effects—like digestive discomfort or headaches—possibly tied to taking higher amounts of these amino acids.
Overall, if you’re seeking a strong formula and value third-party testing, Nutricost could be a solid pick.
5. HumanN SuperBeets
7.9/10
TOTAL RANKING
C+
OVERALL GRADE
PROS
- 500 mg of beetroot.
- Fully herbal.
- Gluten-free, non-GMO & Hypoallergenic.
CONS
- Lacks third party testing.
- Lacks amino acids.
- Some report indigestion.
HumanN’s SuperBeets is a fully herbal, beetroot-focused supplement that has attracted a loyal following thanks to its clean profile—featuring 500 mg of beetroot powder, gluten-free, non-GMO, and hypoallergenic ingredients.
This makes it an appealing choice for those who prefer plant-based products or are particularly mindful of dietary sensitivities.
On the downside, it lacks any amino acids (like L-arginine or L-citrulline), which many users look for when aiming to support nitric oxide levels through multiple pathways. Additionally, there’s no mention of third-party testing, meaning consumers have less reassurance about the product’s potency and purity.
Some users also report indigestion, which may be tied to the beetroot itself or individual sensitivities.
Overall, if you’re looking for a straightforward, herbal approach to nitric oxide support and don’t mind skipping amino acids, HumanN’s SuperBeets could be a decent option.
Conclusion
HumanN’s SuperBeets is a fully herbal, beetroot-focused supplement that has attracted a loyal following thanks to its clean profile—featuring 500 mg of beetroot powder, gluten-free, non-GMO, and hypoallergenic ingredients.
This makes it an appealing choice for those who prefer plant-based products or are particularly mindful of dietary sensitivities.
On the downside, it lacks any amino acids (like L-arginine or L-citrulline), which many users look for when aiming to support nitric oxide levels through multiple pathways. Additionally, there’s no mention of third-party testing, meaning consumers have less reassurance about the product’s potency and purity.
Some users also report indigestion, which may be tied to the beetroot itself or individual sensitivities.
Overall, if you’re looking for a straightforward, herbal approach to nitric oxide support and don’t mind skipping amino acids, HumanN’s SuperBeets could be a decent option.
CITATIONS
- Schwedhelm E, Maas R, Freese R, Jung D, Lukacs Z, Jambrecina A, Spickler W, Schulze F, Böger RH. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol. 2008 Jan;65(1):51-9. doi: 10.1111/j.1365-2125.2007.02990.x. Epub 2007 Jul 27. PMID: 17662090; PMCID: PMC2291275.
- Rhim HC, Kim MS, Park YJ, Choi WS, Park HK, Kim HG, Kim A, Paick SH. The Potential Role of Arginine Supplements on Erectile Dysfunction: A Systemic Review and Meta-Analysis. J Sex Med. 2019 Feb;16(2):223-234. doi: 10.1016/j.jsxm.2018.12.002. Erratum in: J Sex Med. 2020 Mar;17(3):560. doi: 10.1016/j.jsxm.2020.01.021. PMID: 30770070.
- Gonzales JU, Raymond A, Ashley J, Kim Y. Does l-citrulline supplementation improve exercise blood flow in older adults? Exp Physiol. 2017 Dec 1;102(12):1661-1671. doi: 10.1113/EP086587. Epub 2017 Oct 13. PMID: 28940638; PMCID: PMC5999519.
- Bailey SJ, Winyard PG, Vanhatalo A, Blackwell JR, DiMenna FJ, Wilkerson DP, Jones AM. Acute L-arginine supplementation reduces the O2 cost of moderate-intensity exercise and enhances high-intensity exercise tolerance. J Appl Physiol (1985). 2010 Nov;109(5):1394-403. doi: 10.1152/japplphysiol.00503.2010. Epub 2010 Aug 19. PMID: 20724562.
- Barkhidarian B, Khorshidi M, Shab-Bidar S, Hashemi B. Effects of L-citrulline supplementation on blood pressure: A systematic review and meta-analysis. Avicenna J Phytomed. 2019 Jan-Feb;9(1):10-20. PMID: 30788274; PMCID: PMC6369322.
- Hadi A, Arab A, Moradi S, Pantovic A, Clark CCT, Ghaedi E. The effect of l-arginine supplementation on lipid profile: a systematic review and meta-analysis of randomised controlled trials. Br J Nutr. 2019 Nov 14;122(9):1021-1032. doi: 10.1017/S0007114519001855. PMID: 31922465.
What You Will Learn:
- The benefits of a high quality nitric oxide boosters
- What to look for in a nitric oxide boosters
- The top 5 nitric oxide boosterss
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[1] This website is owned and operated by Cosari® and Meo Nutrition® brands.
*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Note: The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a healthcare provider. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Results do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Trademarks utilized on our website belong to their respective owners and no implied or expressed endorsement of our website or services is intended. Rankings can be affected by the relationship Supplement Review has with our picks.
[1] This website is owned and operated by Cosari® and Meo Nutrition® brands.
*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Note: The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a healthcare provider. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Results do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Trademarks utilized on our website belong to their respective owners and no implied or expressed endorsement of our website or services is intended. Rankings can be affected by the relationship Smarter Choices has with our picks.
© 2025 supplement-review.co
All Rights Reserved.