We Reviewed the Top 20 Brands to Find the Best Quality Mushroom Supplements in 2025
Discover the Top-Ranked Mushroom Supplements for 2025
Mushrooms have long been celebrated for their unique health-supporting properties, bridging ancient wisdom with modern science. As interest in these potent natural compounds continues to surge, mushroom supplements have become a go-to option for supporting immune function, cognitive health, energy levels, and overall vitality.
Recognizing their growing popularity, we set out to review the top mushroom supplements available in the U.S. for 2025—highlighting those that blend tradition with innovation to deliver purity, efficacy, and a holistic boost to your wellness routine.
Elisabeth Larsen, Research Specialist
With extensive experience in the field of supplements, Elisabeth stands out as a leading author and researcher. Her expertise is highlighted in our Top 5 Mushroom Supplement review article.
Elisabeth Larsen, Research Specialist
With extensive experience in the field of supplements, Elisabeth stands out as a leading author and researcher. Her expertise is highlighted in our Top 5 Mushroom Supplement review article.
What are Mushroom Supplements?
Mushroom supplements are a natural powerhouse that have been celebrated for centuries in traditional medicine.
Sourced from potent fungi like reishi, lion’s mane, and cordyceps, these extracts have long been used to boost immunity, enhance cognitive function, and support overall vitality.
But modern science is now uncovering even more impressive benefits, sparking renewed interest in these ancient remedies…
Mushroom Supplements Can Help With:
What To Look For In A Mushroom Supplement
Aim for a potent mushroom blend that offers at least 1,000 mg per serving, ensuring that you receive a robust dose of active mushroom extracts rather than a formulation diluted with fillers. Look for products that clearly list a variety of beneficial mushroom species to maximize synergistic effects.
Select a supplement produced in the USA, where stringent quality standards are enforced. Third-party testing by independent laboratories is essential to confirm the purity, potency, and safety of the mushroom extracts.
Opt for a product that comes with a risk-free trial period, ideally featuring a 60-day money-back guarantee. This assurance not only reflects confidence in the supplement's quality but also provides you with the flexibility to test its effectiveness.
A transparent and straightforward return policy is important. Choose brands that make it easy to return the product or obtain a refund if it doesn’t meet your expectations, ensuring a hassle-free customer experience.
What To Avoid
Steer clear of mushroom supplements overloaded with unnecessary additives, fillers, or artificial ingredients. Such extras can dilute the potency of the active compounds and may lead to adverse reactions in some individuals.
Be cautious of products that promise to cure or treat specific ailments or that make unrealistic claims. Rely on supplements that are backed by scientific research, and always consult with a healthcare professional before starting any new supplement regimen.
While affordability is important, choosing the cheapest option without clear, transparent information on ingredients can be risky. Low-cost supplements may compromise quality and efficacy, potentially resulting in a product that is ineffective or even unsafe.
What We Looked Out For:
A comparison of the best mushroom supplements
Meo Nutrition
Micro Ingredients
Drops of Nature
The Genius Brand
Nutricost
Type
Powder
Powder
Gummies
Capsules
Capsules
Dosage per serving
1950 mg
1000 mg
2750 mg
1500 mg
550 mg
Third-party tested
Money back guarantee
24/7 customer service
Price point
$$
$$
$$$
$$$
$
The Top 5 Mushroom Supplements in 2025
9.7/10
TOTAL RANKING
A+
OVERALL GRADE
PROS
- 10 organic mushrooms & adaptogen extracts.
- Produced in the USA at an FDA licensed facility.
- 60 day, risk free, money back guarantee.
- Recommended by doctors.
- Subscription and bulk discounts offered.
- Third-party tested/certificate of analysis (COA).
- No artificial ingredients.
- Ships from Texas.
- Over 400.000+ customers.
CONS
- Due to high demand, it may sometimes be sold out.
- Can only be found online.
After reviewing numerous mushroom supplements, our top pick is Mushroom Plus+ by Meo Nutrition.
This exceptional formula is crafted from 100% organic extracts of 7 mushrooms and 3 adaptogens, delivering nearly 2 grams of potent, natural compounds per serving.
This innovative powder supplement is vegan, non-GMO, and free of the top allergens, ensuring that each serving provides only the best nature has to offer.
In addition to their focus on science and quality in their products, we were also impressed by the quick shipping and support (we received it the next day), and their customer service team was always quick to reply in the chat box.
In terms of value, Mushroom Plus+ is competitively priced with a subscription option reducing the cost to about $0.42 per serving.
Manufactured in a GMP-certified facility and meeting rigorous standards akin to NSF Sports and UDAF Organic certifications, Mushroom Plus+ is backed by strict quality controls. This guarantees a product that is not only effective but also safe and reliable.
Conclusion
After reviewing numerous mushroom supplements, our top pick is Mushroom Plus+ by Meo Nutrition.
This exceptional formula is crafted from 100% organic extracts of 7 mushrooms and 3 adaptogens, delivering nearly 2 grams of potent, natural compounds per serving.
This innovative powder supplement is vegan, non-GMO, and free of the top allergens, ensuring that each serving provides only the best nature has to offer.
In addition to their focus on science and quality in their products, we were also impressed by the quick shipping and support (we received it the next day), and their customer service team was always quick to reply in the chat box.
In terms of value, Mushroom Plus+ is competitively priced with a subscription option reducing the cost to about $0.42 per serving.
Manufactured in a GMP-certified facility and meeting rigorous standards akin to NSF Sports and UDAF Organic certifications, Mushroom Plus+ is backed by strict quality controls. This guarantees a product that is not only effective but also safe and reliable.
2. Micro Ingredients Organic Mega Mushrooms
9.0/10
TOTAL RANKING
A
OVERALL GRADE
PROS
- Blend of 10 different mushroom extract.
- Vegan & 3rd-party lab tested.
- 100% organic blend.
CONS
- Proprietary blend.
- 1000 mg per scoop compared to 1950 mg.
Micro Ingredients is a respected name in the supplement industry, renowned for its commitment to high-quality, organic formulations.
Their Organic Mega Mushrooms supplement features a carefully curated blend of 10 different mushroom extracts, delivering a broad spectrum of bioactive compounds in every serving.
This product is 100% organic, vegan, and rigorously third-party lab tested, ensuring both purity and efficacy.
While the blend is impressive and effective, it's important to note that Organic Mega Mushrooms uses a proprietary formula, offering 1000 mg per scoop compared to some competitors.
Overall, if you prioritize a fully organic, diverse mushroom blend backed by stringent quality controls, Micro Ingredients' Organic Mega Mushrooms is a compelling choice—even if its dosage per serving may be lower than some alternatives.
Conclusion
Micro Ingredients is a respected name in the supplement industry, renowned for its commitment to high-quality, organic formulations.
Their Organic Mega Mushrooms supplement features a carefully curated blend of 10 different mushroom extracts, delivering a broad spectrum of bioactive compounds in every serving.
This product is 100% organic, vegan, and rigorously third-party lab tested, ensuring both purity and efficacy.
While the blend is impressive and effective, it's important to note that Organic Mega Mushrooms uses a proprietary formula, offering 1000 mg per scoop compared to some competitors.
Overall, if you prioritize a fully organic, diverse mushroom blend backed by stringent quality controls, Micro Ingredients' Organic Mega Mushrooms is a compelling choice—even if its dosage per serving may be lower than some alternatives.
3. Drops of Nature Mushroom Gummies
8.7/10
TOTAL RANKING
B+
OVERALL GRADE
PROS
- 100% Vegan.
- Money-back guarantee.
- Gummies may be more convenient for some.
CONS
- Proprietary blend.
- about $0.50 per serving.
Drops of Nature is recognized for its innovative approach to natural supplements, and their Mushroom Gummies are a prime example.
These gummies offer a convenient, chewable way to incorporate the benefits of mushrooms into your daily routine.
Formulated with a proprietary blend, they provide a unique mix of mushroom extracts in a 100% vegan format, ensuring a product that's both ethical and accessible.
With a reassuring money-back guarantee, Drops of Nature’s Mushroom Gummies offer peace of mind for those new to mushroom supplementation.
However, the use of a proprietary blend means that detailed ingredient ratios aren’t disclosed, and the cost is approximately $0.50 per serving which puts them on the slightly pricier side.
Overall, if you value convenience, a vegan formulation, and a risk-free trial period, these Mushroom Gummies are a compelling choice despite the premium price per serving.
Conclusion
Drops of Nature is recognized for its innovative approach to natural supplements, and their Mushroom Gummies are a prime example.
These gummies offer a convenient, chewable way to incorporate the benefits of mushrooms into your daily routine.
Formulated with a proprietary blend, they provide a unique mix of mushroom extracts in a 100% vegan format, ensuring a product that's both ethical and accessible.
With a reassuring money-back guarantee, Drops of Nature’s Mushroom Gummies offer peace of mind for those new to mushroom supplementation.
However, the use of a proprietary blend means that detailed ingredient ratios aren’t disclosed, and the cost is approximately $0.50 per serving which puts them on the slightly pricier side.
Overall, if you value convenience, a vegan formulation, and a risk-free trial period, these Mushroom Gummies are a compelling choice despite the premium price per serving.
4. Genius Mushrooms
8.2/10
TOTAL RANKING
B
OVERALL GRADE
PROS
- Organic extracts.
- Third-party tested.
- Made in the USA.
CONS
- Small blend of 3 mushrooms.
- No money-back guarantee.
- Over $0.70 per servinge.
Genius Mushrooms distinguishes itself through its unwavering commitment to quality and transparency.
Crafted from organic mushroom extracts and produced right here in the USA, each serving is meticulously third-party tested to ensure the highest standards of potency and purity.
This rigorous approach underscores their dedication to providing a premium product that meets strict quality benchmarks.
However, it's important to note that Genius Mushrooms features a modest blend of just 3 mushroom species, which might not satisfy those looking for a broader spectrum of benefits.
Additionally, the absence of a money-back guarantee and a cost exceeding $0.70 per serving position it as the priciest option on our list.
For consumers who value certified organic ingredients and domestic manufacturing, Genius Mushrooms remains an excellent, albeit premium, choice for mushroom supplementation.
Conclusion
Genius Mushrooms distinguishes itself through its unwavering commitment to quality and transparency.
Crafted from organic mushroom extracts and produced right here in the USA, each serving is meticulously third-party tested to ensure the highest standards of potency and purity.
This rigorous approach underscores their dedication to providing a premium product that meets strict quality benchmarks.
However, it's important to note that Genius Mushrooms features a modest blend of just 3 mushroom species, which might not satisfy those looking for a broader spectrum of benefits.
Additionally, the absence of a money-back guarantee and a cost exceeding $0.70 per serving position it as the priciest option on our list.
For consumers who value certified organic ingredients and domestic manufacturing, Genius Mushrooms remains an excellent, albeit premium, choice for mushroom supplementation.
5. Nutricost Mushroom Complex
7.9/10
TOTAL RANKING
C+
OVERALL GRADE
PROS
- Affordable.
- Third-party tested.
- Gluten-free, Non-GMO & Hypoallergenic.
CONS
- Some report stomach discomfort.
- Only 550 mg capsule.
Nutricost Mushroom Complex offers a budget-friendly introduction to mushroom supplementation.
Each 550 mg capsule is third-party tested to ensure quality and purity, while its gluten-free, Non-GMO, and hypoallergenic formulation makes it accessible for a wide range of users.
However, the relatively lower dosage per capsule may not meet the needs of those seeking a more potent effect, and some users have reported stomach discomfort.
Overall, if you’re looking for an affordable, quality-tested option and can manage a milder dosage, Nutricost Mushroom Complex is a practical choice for everyday wellness support.
Conclusion
Nutricost Mushroom Complex offers a budget-friendly introduction to mushroom supplementation.
Each 550 mg capsule is third-party tested to ensure quality and purity, while its gluten-free, Non-GMO, and hypoallergenic formulation makes it accessible for a wide range of users.
However, the relatively lower dosage per capsule may not meet the needs of those seeking a more potent effect, and some users have reported stomach discomfort.
Overall, if you’re looking for an affordable, quality-tested option and can manage a milder dosage, Nutricost Mushroom Complex is a practical choice for everyday wellness support.
CITATIONS
- Deng, G., Lin, H., Seidman, A., Fornier, M., D'Andrea, G., Wesa, K., Yeung, S., Cunningham-Rundles, S., Vickers, A. J., & Cassileth, B. (2009). A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects. Journal of cancer research and clinical oncology, 135(9), 1215–1221. https://doi.org/10.1007/s00432-009-0562-z
- Torkelson, C. J., Sweet, E., Martzen, M. R., Sasagawa, M., Wenner, C. A., Gay, J., Putiri, A., & Standish, L. J. (2012). Phase 1 Clinical Trial of Trametes versicolor in Women with Breast Cancer. ISRN oncology, 2012, 251632. https://doi.org/10.5402/2012/251632
- Gao, Y., Zhou, S., Jiang, W., Huang, M., & Dai, X. (2003). Effects of ganopoly (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patients. Immunological investigations, 32(3), 201–215. https://doi.org/10.1081/imm-120022979
- Nagano, M., Shimizu, K., Kondo, R., Hayashi, C., Sato, D., Kitagawa, K., & Ohnuki, K. (2010). Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomedical research (Tokyo, Japan), 31(4), 231–237. https://doi.org/10.2220/biomedres.31.231
- Tang, W., Gao, Y., Chen, G., Gao, H., Dai, X., Ye, J., Chan, E., Huang, M., & Zhou, S. (2005). A randomized, double-blind and placebo-controlled study of a Ganoderma lucidum polysaccharide extract in neurasthenia. Journal of medicinal food, 8(1), 53–58. https://doi.org/10.1089/jmf.2005.8.53
- Majeed, M., Nagabhushanam, K., & Mundkur, L. (2023). A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study. Medicine, 102(41), e35521. https://doi.org/10.1097/MD.0000000000035521
What You Will Learn:
- The benefits of a high quality mushroom supplement
- What to look for in a mushroom supplement
- The top 5 mushroom supplements
© 2025 supplement-review.co
All Rights Reserved.
[1] This website is owned and operated by Cosari® and Meo Nutrition® brands.
*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Note: The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a healthcare provider. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Results do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Trademarks utilized on our website belong to their respective owners and no implied or expressed endorsement of our website or services is intended. Rankings can be affected by the relationship Supplement Review has with our picks.
[1] This website is owned and operated by Cosari® and Meo Nutrition® brands.
*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Note: The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a healthcare provider. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Results do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Trademarks utilized on our website belong to their respective owners and no implied or expressed endorsement of our website or services is intended. Rankings can be affected by the relationship Smarter Choices has with our picks.
© 2025 supplement-review.co
All Rights Reserved.